Are there any credit cards that cannot be used for mortgage payments? The CardUp Team May 31, 2021 03:13 Please note that credit cards issued by Citibank and American Express cannot be used for mortgage payments. Related articles How do mortgage payments work on CardUp? What types of cards are accepted by CardUp? Are there any credit cards that cannot be used for car loan payments? Will my spend on CardUp earn rewards on my credit card? What supporting documents would I need to upload?