Are there any credit cards that cannot be used for mortgage payments? CardUp Team May 31, 2021 03:13 Please note that credit cards issued by Citibank and American Express cannot be used for mortgage payments. Related articles What types of cards are accepted by CardUp? How do mortgage payments work on CardUp? What supporting documents would I need to upload? What types of payments are supported on an American Express credit card? Promo FAQs: GET225 Offer